A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force
Abstract Background An orthodontic device that moves teeth with pulsating force was invented and underwent a single center, controlled, clinical trial to test its safety and efficacy for treatment. The device has a custom-made thermo-plastic mouthpiece which fits over the teeth with an inflatable si...
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12903-020-01226-z |
| _version_ | 1828816510389321728 |
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| author | Jue Wang Ejvis Lamani Terpsithea Christou Peng Li Chung How Kau |
| author_facet | Jue Wang Ejvis Lamani Terpsithea Christou Peng Li Chung How Kau |
| author_sort | Jue Wang |
| collection | DOAJ |
| description | Abstract Background An orthodontic device that moves teeth with pulsating force was invented and underwent a single center, controlled, clinical trial to test its safety and efficacy for treatment. The device has a custom-made thermo-plastic mouthpiece which fits over the teeth with an inflatable silicone element. A console that measures and controls the pulsating force level in real-time controls the air pressure that delivers a pulsating force. In this study, the effect of the device on root resorption during orthodontic treatment was evaluated using 3D cone beam computed tomography and compared with a control group of patients who received Invisalign treatment. Methods Twenty-eight subjects were enrolled in the investigational arm and 15 in the control group. Subjects were followed until the average score of the mandibular and maxillary teeth achieved a Little’s Irregularity Index of 1.5 mm or less. Results There were no adverse events reported throughout the study for either treatment arm. No clinically significant root resorption was observed for either group. The investigational device did not cause root resorption greater than the control group. Both devices produced a safety profile compared to current orthodontic techniques. Conclusion The investigational device did not produce more root resorption than similar conventional orthodontic appliances. Trial registration ClinicalTrials.gov, NCT03421886 . Registered 12 January 2018 - Retrospectively registered. |
| first_indexed | 2024-12-12T11:06:21Z |
| format | Article |
| id | doaj.art-fff549a16fa54028bb5d3ba991320007 |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-12-12T11:06:21Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-fff549a16fa54028bb5d3ba9913200072022-12-22T00:26:25ZengBMCBMC Oral Health1472-68312020-08-012011710.1186/s12903-020-01226-zA randomized trial on the effects of root resorption after orthodontic treatment using pulsating forceJue Wang0Ejvis Lamani1Terpsithea Christou2Peng Li3Chung How Kau4Department of Orthodontics, School of Dentistry, Univeristy of Alabama at BirminghamDepartment of Orthodontics, School of Dentistry, Univeristy of Alabama at BirminghamDepartment of Orthodontics, School of Dentistry, Univeristy of Alabama at BirminghamSchool of Nursing, University of Alabama at BirminghamDepartment of Orthodontics, School of Dentistry, Univeristy of Alabama at BirminghamAbstract Background An orthodontic device that moves teeth with pulsating force was invented and underwent a single center, controlled, clinical trial to test its safety and efficacy for treatment. The device has a custom-made thermo-plastic mouthpiece which fits over the teeth with an inflatable silicone element. A console that measures and controls the pulsating force level in real-time controls the air pressure that delivers a pulsating force. In this study, the effect of the device on root resorption during orthodontic treatment was evaluated using 3D cone beam computed tomography and compared with a control group of patients who received Invisalign treatment. Methods Twenty-eight subjects were enrolled in the investigational arm and 15 in the control group. Subjects were followed until the average score of the mandibular and maxillary teeth achieved a Little’s Irregularity Index of 1.5 mm or less. Results There were no adverse events reported throughout the study for either treatment arm. No clinically significant root resorption was observed for either group. The investigational device did not cause root resorption greater than the control group. Both devices produced a safety profile compared to current orthodontic techniques. Conclusion The investigational device did not produce more root resorption than similar conventional orthodontic appliances. Trial registration ClinicalTrials.gov, NCT03421886 . Registered 12 January 2018 - Retrospectively registered.http://link.springer.com/article/10.1186/s12903-020-01226-zRadiographic evaluationRoot-crown ratiosClear alignersTooth movementCone beam computed tomography |
| spellingShingle | Jue Wang Ejvis Lamani Terpsithea Christou Peng Li Chung How Kau A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force BMC Oral Health Radiographic evaluation Root-crown ratios Clear aligners Tooth movement Cone beam computed tomography |
| title | A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force |
| title_full | A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force |
| title_fullStr | A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force |
| title_full_unstemmed | A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force |
| title_short | A randomized trial on the effects of root resorption after orthodontic treatment using pulsating force |
| title_sort | randomized trial on the effects of root resorption after orthodontic treatment using pulsating force |
| topic | Radiographic evaluation Root-crown ratios Clear aligners Tooth movement Cone beam computed tomography |
| url | http://link.springer.com/article/10.1186/s12903-020-01226-z |
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