Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis
Laryngopharyngeal reflux (LPR) disease is a condition in which the stomach contents return to the larynx and pharynx via the esophagus, causing mucosal injury. While conventional treatments, such as proton pump inhibitors, have limitations, acupuncture has been shown to reduce LPR symptoms. Howev...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
E-Tree Publishing
2023-08-01
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| Series: | Journal of Acupuncture Research |
| Subjects: |
| _version_ | 1797732766592270336 |
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| author | Jihun Oh Jaewoo Yang Jungmin Yang Minsoo Kang Sukyoung Kim Minjun Lee Jinwoong Lim |
| author_facet | Jihun Oh Jaewoo Yang Jungmin Yang Minsoo Kang Sukyoung Kim Minjun Lee Jinwoong Lim |
| author_sort | Jihun Oh |
| collection | DOAJ |
| description | Laryngopharyngeal reflux (LPR) disease is a condition in which the stomach contents
return to the larynx and pharynx via the esophagus, causing mucosal injury.
While conventional treatments, such as proton pump inhibitors, have limitations,
acupuncture has been shown to reduce LPR symptoms. However, its effectiveness
has not been systematically assessed. This study aimed to systematically evaluate
the effectiveness of acupuncture in treating LPR. We review 10 electronic databases
with a consistent search strategy, and 2 independent reviewers screened the articles
based on the inclusion and exclusion criteria. This study selected and analyzed
7 randomized controlled trials after the screening to assess primary outcomes,
including reflux symptom index and reflux finding score, and secondary outcomes,
including upper and lower esophageal sphincter pressure. The results revealed the
statistically significant effectiveness of acupuncture in combination with conventional
treatment in reducing LPR symptoms compared with conventional treatment
alone. The most commonly used acupuncture points were CV22, ST36, and
LR3. However, the meta-analysis demonstrated low reliability, as assessed using the
GRADE Tool. Further research is needed to improve the evidence and draw clear
conclusions regarding the clinical use of acupuncture for treating LPR. |
| first_indexed | 2024-03-12T12:18:17Z |
| format | Article |
| id | doaj.art-fffa7a2cd47146bb96825674bb26dd2b |
| institution | Directory Open Access Journal |
| issn | 2586-288X 2586-2898 |
| language | English |
| last_indexed | 2024-03-12T12:18:17Z |
| publishDate | 2023-08-01 |
| publisher | E-Tree Publishing |
| record_format | Article |
| series | Journal of Acupuncture Research |
| spelling | doaj.art-fffa7a2cd47146bb96825674bb26dd2b2023-08-30T07:32:12ZengE-Tree PublishingJournal of Acupuncture Research2586-288X2586-28982023-08-0140318820010.13045/jar.2023.00087Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-AnalysisJihun Oh0Jaewoo Yang1Jungmin Yang2Minsoo Kang3Sukyoung Kim4Minjun Lee5Jinwoong Lim6Department of Acupuncture and Moxibustion, Mokhuri Neck and Back Hospital, Seoul, KoreaDepartment of Acupuncture and Moxibustion, Mokhuri Neck and Back Hospital, Seoul, KoreaDepartment of Korean Internal Medicine, Mokhuri Neck and Back Hospital, Seoul, KoreaMokhuri Neck and Back Hospital, Seoul, KoreaMokhuri Neck and Back Hospital, Seoul, KoreaMokhuri Neck and Back Hospital, Seoul, KoreaDepartment of Acupuncture and Moxibustion, Wonkwang University Gwangju Korean Medicine Hospital, Gwangju, KoreaLaryngopharyngeal reflux (LPR) disease is a condition in which the stomach contents return to the larynx and pharynx via the esophagus, causing mucosal injury. While conventional treatments, such as proton pump inhibitors, have limitations, acupuncture has been shown to reduce LPR symptoms. However, its effectiveness has not been systematically assessed. This study aimed to systematically evaluate the effectiveness of acupuncture in treating LPR. We review 10 electronic databases with a consistent search strategy, and 2 independent reviewers screened the articles based on the inclusion and exclusion criteria. This study selected and analyzed 7 randomized controlled trials after the screening to assess primary outcomes, including reflux symptom index and reflux finding score, and secondary outcomes, including upper and lower esophageal sphincter pressure. The results revealed the statistically significant effectiveness of acupuncture in combination with conventional treatment in reducing LPR symptoms compared with conventional treatment alone. The most commonly used acupuncture points were CV22, ST36, and LR3. However, the meta-analysis demonstrated low reliability, as assessed using the GRADE Tool. Further research is needed to improve the evidence and draw clear conclusions regarding the clinical use of acupuncture for treating LPR.acupuncturelaryngopharyngeal refluxmeta-analysissystematic review |
| spellingShingle | Jihun Oh Jaewoo Yang Jungmin Yang Minsoo Kang Sukyoung Kim Minjun Lee Jinwoong Lim Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis Journal of Acupuncture Research acupuncture laryngopharyngeal reflux meta-analysis systematic review |
| title | Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis |
| title_full | Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis |
| title_fullStr | Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis |
| title_short | Effectiveness of Acupuncture for Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis |
| title_sort | effectiveness of acupuncture for laryngopharyngeal reflux disease a systematic review and meta analysis |
| topic | acupuncture laryngopharyngeal reflux meta-analysis systematic review |
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