Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

tRNA (tRNA) is a key molecule used for protein synthesis, with multiple points of stress-induced regulation that can include transcription, transcript processing, localization and ribonucleoside base modification. Enzyme-catalyzed modification of tRNA occurs at a number of base and sugar positions a...

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Bibliographic Details
Main Authors: Endres, Lauren, Dedon, Peter C., Begley, Thomas J.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Landes Bioscience 2015
Online Access:http://hdl.handle.net/1721.1/100248
https://orcid.org/0000-0003-0011-3067