A computational framework for identifying design guidelines to increase the penetration of targeted nanoparticles into tumors
Targeted nanoparticles are increasingly being engineered for the treatment of cancer. By design, they can passively accumulate in tumors, selectively bind to targets in their environment, and deliver localized treatments. However, the penetration of targeted nanoparticles deep into tissue can be hin...
Main Authors: | Hauert, Sabine, Berman, Spring, Nagpal, Radhika, Bhatia, Sangeeta N |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/100420 https://orcid.org/0000-0002-1293-2097 |
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