Alzheimer's loci: epigenetic associations and interaction with genetic factors

Alzheimer's loci: epigenetic associations and interaction with genetic factors

Objective We explore the role of DNA methylation in Alzheimer's disease (AD). To elucidate where DNA methylation falls along the causal pathway linking risk factors to disease, we examine causal models to assess its role in the pathology of AD. Methods DNA methylation profiles were generated...

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Bibliographic Details
Main Authors: Chibnik, Lori B., Yu, Lei, Srivastava, Gyan, Schneider, Julie A., Kellis, Manolis, Bennett, David A., De Jager, Philip L., Eaton, Matthew Lucas
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: American Neurological Association 2016
Online Access:http://hdl.handle.net/1721.1/100782
https://orcid.org/0000-0002-8305-9125

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