Streptococcus Pneumoniae Secretes Hydrogen Peroxide Leading to DNA Damage and Apoptosis in Lung Cells

Streptococcus pneumoniae is a leading cause of pneumonia and one of the most common causes of death globally. The impact of S. pneumoniae on host molecular processes that lead to detrimental pulmonary consequences is not fully understood. Here, we show that S. pneumoniae induces toxic DNA double-str...

Full description

Bibliographic Details
Main Authors: Rai, Prashant, Tay, Ian Jun Jie, Li, Na, Ackerman, Shelley, He, Fang, Kwang, Jimmy, Chow, Vincent T., Engelward, Bevin P., Parrish, Marcus Curtis, Tay, Jun Jie Ian
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2016
Online Access:http://hdl.handle.net/1721.1/100789
https://orcid.org/0000-0002-5472-3621
https://orcid.org/0000-0002-7149-9369