Streptococcus Pneumoniae Secretes Hydrogen Peroxide Leading to DNA Damage and Apoptosis in Lung Cells
Streptococcus pneumoniae is a leading cause of pneumonia and one of the most common causes of death globally. The impact of S. pneumoniae on host molecular processes that lead to detrimental pulmonary consequences is not fully understood. Here, we show that S. pneumoniae induces toxic DNA double-str...
Main Authors: | Rai, Prashant, Tay, Ian Jun Jie, Li, Na, Ackerman, Shelley, He, Fang, Kwang, Jimmy, Chow, Vincent T., Engelward, Bevin P., Parrish, Marcus Curtis, Tay, Jun Jie Ian |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2016
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Online Access: | http://hdl.handle.net/1721.1/100789 https://orcid.org/0000-0002-5472-3621 https://orcid.org/0000-0002-7149-9369 |
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