Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alon...

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Main Authors: Hook, Andrew L., Chang, Chien-Yi, Scurr, David J., Williams, Paul, Davies, Martyn C., Alexander, Morgan R., Anderson, Daniel Griffith, Langer, Robert S
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Wiley Blackwell 2016
Online Access:http://hdl.handle.net/1721.1/101141
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492
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author Hook, Andrew L.
Chang, Chien-Yi
Scurr, David J.
Williams, Paul
Davies, Martyn C.
Alexander, Morgan R.
Anderson, Daniel Griffith
Langer, Robert S
author2 Harvard University--MIT Division of Health Sciences and Technology
author_facet Harvard University--MIT Division of Health Sciences and Technology
Hook, Andrew L.
Chang, Chien-Yi
Scurr, David J.
Williams, Paul
Davies, Martyn C.
Alexander, Morgan R.
Anderson, Daniel Griffith
Langer, Robert S
author_sort Hook, Andrew L.
collection MIT
description The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone; rather, the surface composition of the polymer plays the key role.
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spelling mit-1721.1/1011412022-09-26T12:06:03Z Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment Hook, Andrew L. Chang, Chien-Yi Scurr, David J. Williams, Paul Davies, Martyn C. Alexander, Morgan R. Anderson, Daniel Griffith Langer, Robert S Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Chemical Engineering Koch Institute for Integrative Cancer Research at MIT Langer, Robert Anderson, Daniel Griffith The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone; rather, the surface composition of the polymer plays the key role. Wellcome Trust (London, England) (Grant 085245) National Institutes of Health (U.S.) (Grant R01 DE016516) 2016-02-09T19:05:08Z 2016-02-09T19:05:08Z 2014-02 2013-12 Article http://purl.org/eprint/type/JournalArticle 21922640 http://hdl.handle.net/1721.1/101141 Hook, Andrew L., Chien-Yi Chang, David J. Scurr, Robert Langer, Daniel G. Anderson, Paul Williams, Martyn C. Davies, and Morgan R. Alexander. “ Thermally Switchable Polymers Achieve Controlled Escherichia Coli Detachment .” Adv. Healthcare Mater. 3, no. 7 (February 4, 2014): 1020–1025. https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492 en_US http://dx.doi.org/10.1002/adhm.201300518 Advanced Healthcare Materials Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wiley Blackwell PMC
spellingShingle Hook, Andrew L.
Chang, Chien-Yi
Scurr, David J.
Williams, Paul
Davies, Martyn C.
Alexander, Morgan R.
Anderson, Daniel Griffith
Langer, Robert S
Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
title Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
title_full Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
title_fullStr Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
title_full_unstemmed Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
title_short Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
title_sort thermally switchable polymers achieve controlled escherichia coli detachment
url http://hdl.handle.net/1721.1/101141
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492
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