Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

The efficacy of implanted biomedical devices is often compromised by host recognition and subsequent foreign body responses. Here, we demonstrate the role of the geometry of implanted materials on their biocompatibility in vivo. In rodent and non-human primate animal models, implanted spheres 1.5 mm...

Full description

Bibliographic Details
Main Authors: Veiseh, Omid, Ma, Minglin, Tam, Hok Hei, Li, Jie, Langan, Erin, Wyckoff, Jeffrey, Loo, Whitney S., Jhunjhunwala, Siddharth, Chiu, Alan, Tang, Katherine, Hollister-Lock, Jennifer, Bochenek, Matthew, Mendoza-Elias, Joshua, Wang, Yong, Qi, Merigeng, Lavin, Danya M., Dholakia, Nimit, Thakrar, Raj, Weir, Gordon C., Oberholzer, Jose, Greiner, Dale L., Vegas, Arturo, Bader, Andrew, Anderson, Daniel Griffith, Lacik, Igor, Thankrar, Raj, Doloff, Joshua C, Siebert, Sean M, Chen, Michael Y, Langer, Robert S, Aresta-Dasilva, Stephanie K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101142
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-4323-3264
https://orcid.org/0000-0003-1520-4180
https://orcid.org/0000-0001-8223-035X
https://orcid.org/0000-0001-9522-8208
https://orcid.org/0000-0002-2358-0330
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0002-5840-2366
https://orcid.org/0000-0003-4255-0492

Similar Items