Crosslinked linear polyethylenimine enhances delivery of DNA to the cytoplasm

Crosslinked polyethylenimines (PEIs) have been frequently examined over the past decade since they can maintain the transfection efficiency of commercially available, 25 k branched PEI, but exhibit less cytotoxicity. The argument is often made that the degradability of such polymers, generally synth...

Full description

Bibliographic Details
Main Authors: Bonner, Daniel K., Zhao, Xiaoyong, Buss, Hilda, Langer, Robert S, Hammond, Paula T
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101176
https://orcid.org/0000-0003-4255-0492