Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics

Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics

Antisense oligonucleotides can be employed as a potential approach to effectively treat cancer. However, the inherent instability and inefficient systemic delivery methods for antisense therapeutics remain major challenges to their clinical application. Here, we present a polymerized oligonucleotide...

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Bibliographic Details
Main Authors:	Roh, Young Hoon, Lee, Jong Bum, Morton, Stephen Winford, Poon, Zhiyong, Hong, Jinkee, Yamin, Inbar, Bonner, Daniel K., Shopsowitz, Kevin, Hammond, Paula T, Dreaden, Erik
Other Authors:	Massachusetts Institute of Technology. Department of Chemical Engineering
Format:	Article
Language:	en_US
Published:	American Chemical Society (ACS) 2016
Online Access:	http://hdl.handle.net/1721.1/101178 https://orcid.org/0000-0002-4954-8443 https://orcid.org/0000-0003-3988-0837 https://orcid.org/0000-0003-3243-8536

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