Mechanism of active substrate delivery by the AAA+ protease adaptor CIpS

Mechanism of active substrate delivery by the AAA+ protease adaptor CIpS

Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2015.

Bibliographic Details
Main Author:	Rivera-Rivera, Izarys
Other Authors:	Tania A. Baker and Robert T. Sauer.
Format:	Thesis
Language:	eng
Published:	Massachusetts Institute of Technology 2016
Subjects:	Biology.
Online Access:	http://hdl.handle.net/1721.1/101352

Similar Items

Mechanisms of CipS reprogramming of the AAA+ protease CipAP
by: Torres-Delgado, Amaris
Published: (2016)

Interaction between the AAA+ protease CIpXP and the adaptor protein SspB
by: Chowdhury, Tahmeena
Published: (2010)

The N-end rule degradation pathway : substrate recognition and staged delivery to the CIpAP protease by the CIpS adaptor protein
by: Román Hernández, Giselle
Published: (2011)

The IbpA and IbpB small heat-shock proteins are substrates of the AAA plus Lon protease
by: Bissonnette, Sarah A., et al.
Published: (2011)

Insights into the role and mechanism of the AAA+ adaptor Clps
by: Hou, Jennifer Yuan
Published: (2009)

Mechanisms of substrate recognition by the AAA+ protease HslUV
by: Sundar, Shankar
Published: (2011)

The ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP Protease
by: Hou, Jennifer Y., et al.
Published: (2014)

Specificity and regulation of substrate degradation for a AAA+ protease
by: Farrell, Christopher Mark
Published: (2007)

AAA+ protease-adaptor structures reveal altered conformations and ring specialization
by: Kim, Sora, et al.
Published: (2022)

Functional and structural studies of AAA+ proteases
by: Baytshtok, Vladimir
Published: (2017)

Mechanistic studies of a AAA+ protease
by: Nager, Andrew R. (Andrew Ross)
Published: (2013)

The role of the N domain in substrate binding, oligomerization, and allosteric regulation of the AAA+ Lon protease
by: Wohlever, Matthew L
Published: (2013)

Remodeling of a delivery complex allows ClpS-mediated degradation of N-degron substrates
by: Baker, Tania, et al.
Published: (2017)

The Intrinsically Disordered N-terminal Extension of the ClpS Adaptor Reprograms Its Partner AAA + ClpAP Protease
by: Torres-Delgado, Amaris, et al.
Published: (2021)

Multistep substrate binding and engagement by the AAA+ ClpXP protease
by: Saunders, Reuben A, et al.
Published: (2021)

Substrate specificity of [alpha]-proteobacterial N-end rule adaptors
by: Stein, Benjamin J. (Benjamin Joseph)
Published: (2016)

Distinct quaternary structures of the AAA+ Lon protease control substrate degradation
by: Vieux (Kloss), Ellen, et al.
Published: (2013)

N domain of the Lon AAA+ protease controls assembly and substrate choice
by: Brown, Breann L., et al.
Published: (2022)

Roles of the N domain of the AAA+ Lon protease in substrate recognition, allosteric regulation and chaperone activity
by: Baker, Tania, et al.
Published: (2015)

Auto-tethering as a selection mechanism for recognition of multimeric substrates by the AAA+ unfoldase ClpX
by: Abdelhakim, Aliaa H. (Aliaa Hamid)
Published: (2014)

Substrate specificity, active-site residues, and function of the Tsp protease
by: Keiler, Kenneth Charles
Published: (2007)

Structural Principles of Substrate Recognition and Unfolding by the ClpAP and ClpXP AAA+ Proteases
by: Kim, Sora
Published: (2022)

Degradation of the E. coli small heat-shock proteins by the AAA+ protease lon : significance to protein quality-control
by: Bissonnette, Sarah Ayano
Published: (2010)

Multiple Sequence Signals Direct Recognition and Degradation of Protein Substrates by the AAA+ Protease HslUV
by: Sundar, Shankar, et al.
Published: (2015)

Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease
by: Kasal, Meghann
Published: (2023)

Cryo-EM structure of the entire FtsH-HflKC AAA protease complex
by: Qiao, Zhu, et al.
Published: (2022)

Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug
by: Baytshtok, Vladimir, et al.
Published: (2021)

Polypeptide translocation by the AAA+ ClpXP protease machine
by: Barkow, Sarah R., et al.
Published: (2012)

Substrate selection by the ClpXP protease : a tail of destruction
by: Flynn, Julia M., 1976-
Published: (2005)

Characterization of the ADA/GCN5 transcriptional adaptor complex
by: Horiuchi, Junjiro
Published: (2009)

Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines
by: Olivares, Adrian O., et al.
Published: (2017)

Dissecting the steps of substrate processing by the energy-dependent protease ClpXP
by: Siddiqui, Samia M. (Siddiqui Mohammed), 1977-
Published: (2006)

Genetic and biochemical characterization of the ADAs, a transcriptional adaptor complex
by: Silverman, Neal Scott
Published: (2008)

Examination of two remarkable AAA+ proteases: unraveling substrate-enzyme interactions of the double-ringed ClpAP and direct thermal activation of HslUV proteolysis
by: Shih, Tsai-Ting (Irene)
Published: (2024)

Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease
by: Shin, Yongdae, et al.
Published: (2010)

Assaying the kinetics of protein denaturation catalyzed by AAA+ unfolding machines and proteases
by: Baytshtok, Vladimir, et al.
Published: (2015)

The role of the adaptor protein CbbO in the Rubisco activation system of chemoautotrophic bacteria
by: Liu, Di
Published: (2019)

Modular and coordinated activity of AAA+ active sites in the double-ring ClpA unfoldase of the ClpAP protease
by: Zuromski, Kristin L, et al.
Published: (2021)

Isolation of GCN5 and ADA5 in a selection for transcriptional adaptors
by: Marcus, Gregory A
Published: (2008)

Molecular mechanism of PilZ adaptor protein mediated cyclic di-GMP signaling
by: Xin, Lingyi
Published: (2018)