Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked in single cells, it has not yet been possible to determine whether these mRNAs are actively translating. Therefore, we imaged single β-actin m...

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Bibliographic Details
Main Authors:	Katz, Zachary B, English, Brian P, Lionnet, Timothee, Yoon, Young J, Monnier, Nilah, Ovryn, Ben, Bathe, Mark, Singer, Robert H
Other Authors:	Massachusetts Institute of Technology. Department of Biological Engineering
Format:	Article
Language:	en_US
Published:	eLife Sciences Publications, Ltd. 2016
Online Access:	http://hdl.handle.net/1721.1/101427 https://orcid.org/0000-0002-6199-6855

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