Site-Directed Mutagenesis to Improve Sensitivity of a Synthetic Two-Component Signaling System
Two-component signaling (2CS) systems enable bacterial cells to respond to changes in their local environment, often using a membrane-bound sensor protein and a cytoplasmic responder protein to regulate gene expression. Previous work has shown that Escherichia coli’s natural EnvZ/OmpR 2CS could be m...
Main Authors: | , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2016
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Online Access: | http://hdl.handle.net/1721.1/101670 https://orcid.org/0000-0001-9483-1291 |