H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in embryonic stem cells (ESCs) to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. Here, we investigate the function of H2A.Z.1 monoubiquitylation (H2A.Z.1ub) by...

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Bibliographic Details
Main Authors: Surface, Lauren E., Fields, Paul A., Subramanian, Vidya, Behmer, Russell, Udeshi, Namrata, Peach, Sally E., Carr, Steven A., Jaffe, Jacob D., Fields, Paul A., Boyer, Laurie Ann, Surface, Lauren Elizabeth
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/101695
https://orcid.org/0000-0002-9608-6464
https://orcid.org/0000-0003-3491-4962

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