Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements
MicroRNAs (miRNAs) regulate diverse biological processes by repressing mRNAs, but their modest effects on direct targets, together with their participation in larger regulatory networks, make it challenging to delineate miRNA-mediated effects. Here, we describe an approach to characterizing miRNA-re...
Main Authors: | Gurtan, Allan M., JnBaptiste, Courtney K., Bosson, Andrew, Milani, Pamela, Matthews, Bryan J., Yap, Yoon S., Sharp, Phillip A., Fraenkel, Ernest, Gosline, Sara Jane Calafell, Gurtan, Allan M., Dalin, Simona, JnBaptiste, Courtney Kenneil, Matthews, Bryan, Yap, Yoon Sing |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/101699 https://orcid.org/0000-0003-0250-0474 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0001-5024-9718 https://orcid.org/0000-0001-9249-8181 https://orcid.org/0000-0002-6534-4774 https://orcid.org/0000-0001-8353-9316 |
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