Bistability of a coupled Aurora B kinase-phosphatase system in cell division
Aurora B kinase, a key regulator of cell division, localizes to specific cellular locations, but the regulatory mechanisms responsible for phosphorylation of substrates located remotely from kinase enrichment sites are unclear. Here, we provide evidence that this activity at a distance depends on bo...
Main Authors: | Godzi, Maxim, Calderon, Abram, Stamatov, Rumen, Zaytsev, Anatoly V., Segura-Pena, Dario, Ballister, Edward R., Mayo, Alyssa M., Black, Ben E., Ataullakhanov, Fazly I., Lampson, Michael A., Grishchuk, Ekaterina L., Peterson, Laura B |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
eLife Sciences Publications, Ltd.
2016
|
Online Access: | http://hdl.handle.net/1721.1/101721 |
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