A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

We introduce a microfluidic platform that enables off-chip single-cell RNA-seq after multi-generational lineage tracking under controlled culture conditions. We use this platform to generate whole-transcriptome profiles of primary, activated murine CD8+ T-cell and lymphocytic leukemia cell line line...

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Bibliographic Details
Main Authors: Li, Jennifer W., Genshaft, Alex S., de Riba Borrajo, Jacob, Shalek, Alex K., Kimmerling, Robert John, Kazer, Samuel Weisgurt, Payer, Kristofor Robert, Borrajo, Jacob de Riba, Blainey, Paul C, Irvine, Darrell J, Manalis, Scott R, Szeto, Gregory, Shalek, Alexander K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/101730
https://orcid.org/0000-0002-7380-9594
https://orcid.org/0000-0001-5223-9433
https://orcid.org/0000-0003-3079-5134
https://orcid.org/0000-0001-7604-1333
https://orcid.org/0000-0003-3552-8182
https://orcid.org/0000-0001-7014-3830
https://orcid.org/0000-0001-9939-764X

Internet

http://hdl.handle.net/1721.1/101730
https://orcid.org/0000-0002-7380-9594
https://orcid.org/0000-0001-5223-9433
https://orcid.org/0000-0003-3079-5134
https://orcid.org/0000-0001-7604-1333
https://orcid.org/0000-0003-3552-8182
https://orcid.org/0000-0001-7014-3830
https://orcid.org/0000-0001-9939-764X

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