Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome

Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome

Many neuropsychiatric symptoms of fragile X syndrome (FXS) are believed to be a consequence of altered regulation of protein synthesis at synapses. We discovered that lovastatin, a drug that is widely prescribed for the treatment of high cholesterol, can correct excess hippocampal protein synthesis...

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Bibliographic Details
Main Authors: Chuang, Shih-Chieh, Chubykin, Alexander A., Sidorov, Michael, Bianchi, Riccardo, Wong, Robert K.S., Osterweil, Emily, Bear, Mark, Chubykin, Alexander A.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/102250
https://orcid.org/0000-0003-0582-2284

Internet

http://hdl.handle.net/1721.1/102250
https://orcid.org/0000-0003-0582-2284

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