Aneuploidy-induced cellular stresses limit autophagic degradation

An unbalanced karyotype, a condition known as aneuploidy, has a profound impact on cellular physiology and is a hallmark of cancer. Aneuploid cells experience a number of stresses that are caused by aneuploidy-induced proteomic changes. How the aneuploidy-associated stresses affect cells and whether...

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Bibliographic Details
Main Authors: Santaguida, Stefano, Vasile, Eliza, White, Eileen, Amon, Angelika B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2016
Online Access:http://hdl.handle.net/1721.1/102257
https://orcid.org/0000-0002-1501-6190
https://orcid.org/0000-0001-9837-0314