Aneuploidy-induced cellular stresses limit autophagic degradation
An unbalanced karyotype, a condition known as aneuploidy, has a profound impact on cellular physiology and is a hallmark of cancer. Aneuploid cells experience a number of stresses that are caused by aneuploidy-induced proteomic changes. How the aneuploidy-associated stresses affect cells and whether...
Main Authors: | Santaguida, Stefano, Vasile, Eliza, White, Eileen, Amon, Angelika B |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2016
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Online Access: | http://hdl.handle.net/1721.1/102257 https://orcid.org/0000-0002-1501-6190 https://orcid.org/0000-0001-9837-0314 |
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