FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

Background Genomewide association studies can be used to identify disease-relevant genomic regions, but interpretation of the data is challenging. The FTO region harbors the strongest genetic association with obesity, yet the mechanistic basis of this association remains elusive. Methods We exami...

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Bibliographic Details
Main Authors: Claussnitzer, Melina, Dankel, Simon N., Kim, Kyoung-Han, Quon, Gerald, Meuleman, Wouter, Haugen, Christine, Glunk, Viktoria, Sousa, Isabel S., Beaudry, Jacqueline L., Puviindran, Vijitha, Liu, Jannel, Svensson, Per-Arne, Hsu, Yi-Hsiang, Drucker, Daniel J., Mellgren, Gunnar, Hui, Chi-Chung, Hauner, Hans, Kellis, Manolis, Abdennur, Nezar Alexander
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: New England Journal of Medicine 2016
Online Access:http://hdl.handle.net/1721.1/102270
https://orcid.org/0000-0002-1716-0153
https://orcid.org/0000-0003-2450-736X
https://orcid.org/0000-0002-1196-5401
https://orcid.org/0000-0001-5814-0864

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