Subcortical connections of area V4 in the macaque
Area V4 has numerous, topographically organized connections with multiple cortical areas, some of which are important for spatially organized visual processing, and others which seem important for spatial attention. Although the topographic organization of V4's connections with other cortical a...
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| Format: | Article |
| Language: | en_US |
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Wiley Blackwell
2016
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| Online Access: | http://hdl.handle.net/1721.1/102399 https://orcid.org/0000-0002-5938-4227 |
| _version_ | 1826194146722840576 |
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| author | Gattass, Ricardo Galkin, Thelma W. Desimone, Robert Ungerleider, Leslie G. |
| author2 | McGovern Institute for Brain Research at MIT |
| author_facet | McGovern Institute for Brain Research at MIT Gattass, Ricardo Galkin, Thelma W. Desimone, Robert Ungerleider, Leslie G. |
| author_sort | Gattass, Ricardo |
| collection | MIT |
| description | Area V4 has numerous, topographically organized connections with multiple cortical areas, some of which are important for spatially organized visual processing, and others which seem important for spatial attention. Although the topographic organization of V4's connections with other cortical areas has been established, the detailed topography of its connections with subcortical areas is unclear. We therefore injected retrograde and anterograde tracers in different topographical regions of V4 in nine macaques to determine the organization of its subcortical connections. The injection sites included representations ranging from the fovea to far peripheral eccentricities in both the upper and lower visual fields. The topographically organized connections of V4 included bidirectional connections with four subdivisions of the pulvinar, two subdivisions of the claustrum, and the interlaminar portions of the lateral geniculate nucleus, and efferent projections to the superficial and intermediate layers of the superior colliculus, the thalamic reticular nucleus, and the caudate nucleus. All of these structures have a possible role in spatial attention. The nontopographic, or converging, connections included bidirectional connections with the lateral nucleus of the amygdala, afferent inputs from the dorsal raphe, median raphe, locus coeruleus, ventral tegmentum and nucleus basalis of Meynert, and efferent projections to the putamen. Any role of these structures in attention may be less spatially specific. |
| first_indexed | 2024-09-23T09:51:39Z |
| format | Article |
| id | mit-1721.1/102399 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:51:39Z |
| publishDate | 2016 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/1023992022-09-26T14:09:55Z Subcortical connections of area V4 in the macaque Gattass, Ricardo Galkin, Thelma W. Desimone, Robert Ungerleider, Leslie G. McGovern Institute for Brain Research at MIT Desimone, Robert Area V4 has numerous, topographically organized connections with multiple cortical areas, some of which are important for spatially organized visual processing, and others which seem important for spatial attention. Although the topographic organization of V4's connections with other cortical areas has been established, the detailed topography of its connections with subcortical areas is unclear. We therefore injected retrograde and anterograde tracers in different topographical regions of V4 in nine macaques to determine the organization of its subcortical connections. The injection sites included representations ranging from the fovea to far peripheral eccentricities in both the upper and lower visual fields. The topographically organized connections of V4 included bidirectional connections with four subdivisions of the pulvinar, two subdivisions of the claustrum, and the interlaminar portions of the lateral geniculate nucleus, and efferent projections to the superficial and intermediate layers of the superior colliculus, the thalamic reticular nucleus, and the caudate nucleus. All of these structures have a possible role in spatial attention. The nontopographic, or converging, connections included bidirectional connections with the lateral nucleus of the amygdala, afferent inputs from the dorsal raphe, median raphe, locus coeruleus, ventral tegmentum and nucleus basalis of Meynert, and efferent projections to the putamen. Any role of these structures in attention may be less spatially specific. National Institute of Mental Health (U.S.). Intramural Research Program National Institutes of Health (U.S.) (Grant R01EY017292) 2016-05-04T15:51:46Z 2016-05-04T15:51:46Z 2014-04 2013-11 Article http://purl.org/eprint/type/JournalArticle 00219967 1096-9861 http://hdl.handle.net/1721.1/102399 Gattass, Ricardo, Thelma W. Galkin, Robert Desimone, and Leslie G. Ungerleider. “Subcortical Connections of Area V4 in the Macaque.” J. Comp. Neurol. 522, no. 8 (April 3, 2014): 1941–1965. © 2013 Wiley Periodicals, Inc. https://orcid.org/0000-0002-5938-4227 en_US http://dx.doi.org/10.1002/cne.23513 Journal of Comparative Neurology Creative Commons Attribution http://creativecommons.org/licenses/by/3.0/ application/pdf Wiley Blackwell Wiley |
| spellingShingle | Gattass, Ricardo Galkin, Thelma W. Desimone, Robert Ungerleider, Leslie G. Subcortical connections of area V4 in the macaque |
| title | Subcortical connections of area V4 in the macaque |
| title_full | Subcortical connections of area V4 in the macaque |
| title_fullStr | Subcortical connections of area V4 in the macaque |
| title_full_unstemmed | Subcortical connections of area V4 in the macaque |
| title_short | Subcortical connections of area V4 in the macaque |
| title_sort | subcortical connections of area v4 in the macaque |
| url | http://hdl.handle.net/1721.1/102399 https://orcid.org/0000-0002-5938-4227 |
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