Normal Midbrain Dopaminergic Neuron Development and Function in miR-133b Mutant Mice

Normal Midbrain Dopaminergic Neuron Development and Function in miR-133b Mutant Mice

Midbrain dopaminergic (mDA) neurons control movement and emotion, and their degeneration leads to motor and cognitive defects in Parkinson's disease (PD). miR-133b is a conserved microRNA that is thought to regulate mDA neuron differentiation by targeting Pitx3, a transcription factor required...

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Bibliographic Details
Main Authors: Heyer, Mary P., Pani, Amar K., Smeyne, Richard J., Kenny, Paul K., Feng, Guoping
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2016
Online Access:http://hdl.handle.net/1721.1/102412
https://orcid.org/0000-0002-8021-277X

Internet

http://hdl.handle.net/1721.1/102412
https://orcid.org/0000-0002-8021-277X

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