Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques
The existence of color-processing regions in the human ventral visual pathway (VVP) has long been known from patient and imaging studies, but their location in the cortex relative to other regions, their selectivity for color compared with other properties (shape and object category), and their rela...
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| Format: | Article |
| Language: | en_US |
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Society for Neuroscience
2016
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| Online Access: | http://hdl.handle.net/1721.1/102459 https://orcid.org/0000-0002-4514-0299 https://orcid.org/0000-0003-3853-7885 |
| _version_ | 1811079751059636224 |
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| author | Lafer-Sousa, Rosa Conway, Bevil Kanwisher, Nancy |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Lafer-Sousa, Rosa Conway, Bevil Kanwisher, Nancy |
| author_sort | Lafer-Sousa, Rosa |
| collection | MIT |
| description | The existence of color-processing regions in the human ventral visual pathway (VVP) has long been known from patient and imaging studies, but their location in the cortex relative to other regions, their selectivity for color compared with other properties (shape and object category), and their relationship to color-processing regions found in nonhuman primates remain unclear. We addressed these questions by scanning 13 subjects with fMRI while they viewed two versions of movie clips (colored, achromatic) of five different object classes (faces, scenes, bodies, objects, scrambled objects). We identified regions in each subject that were selective for color, faces, places, and object shape, and measured responses within these regions to the 10 conditions in independently acquired data. We report two key findings. First, the three previously reported color-biased regions (located within a band running posterior–anterior along the VVP, present in most of our subjects) were sandwiched between face-selective cortex and place-selective cortex, forming parallel bands of face, color, and place selectivity that tracked the fusiform gyrus/collateral sulcus. Second, the posterior color-biased regions showed little or no selectivity for object shape or for particular stimulus categories and showed no interaction of color preference with stimulus category, suggesting that they code color independently of shape or stimulus category; moreover, the shape-biased lateral occipital region showed no significant color bias. These observations mirror results in macaque inferior temporal cortex (Lafer-Sousa and Conway, 2013), and taken together, these results suggest a homology in which the entire tripartite face/color/place system of primates migrated onto the ventral surface in humans over the course of evolution. |
| first_indexed | 2024-09-23T11:19:58Z |
| format | Article |
| id | mit-1721.1/102459 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:19:58Z |
| publishDate | 2016 |
| publisher | Society for Neuroscience |
| record_format | dspace |
| spelling | mit-1721.1/1024592022-09-27T18:48:14Z Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques Lafer-Sousa, Rosa Conway, Bevil Kanwisher, Nancy Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT Lafer-Sousa, Rosa Conway, Bevil Kanwisher, Nancy The existence of color-processing regions in the human ventral visual pathway (VVP) has long been known from patient and imaging studies, but their location in the cortex relative to other regions, their selectivity for color compared with other properties (shape and object category), and their relationship to color-processing regions found in nonhuman primates remain unclear. We addressed these questions by scanning 13 subjects with fMRI while they viewed two versions of movie clips (colored, achromatic) of five different object classes (faces, scenes, bodies, objects, scrambled objects). We identified regions in each subject that were selective for color, faces, places, and object shape, and measured responses within these regions to the 10 conditions in independently acquired data. We report two key findings. First, the three previously reported color-biased regions (located within a band running posterior–anterior along the VVP, present in most of our subjects) were sandwiched between face-selective cortex and place-selective cortex, forming parallel bands of face, color, and place selectivity that tracked the fusiform gyrus/collateral sulcus. Second, the posterior color-biased regions showed little or no selectivity for object shape or for particular stimulus categories and showed no interaction of color preference with stimulus category, suggesting that they code color independently of shape or stimulus category; moreover, the shape-biased lateral occipital region showed no significant color bias. These observations mirror results in macaque inferior temporal cortex (Lafer-Sousa and Conway, 2013), and taken together, these results suggest a homology in which the entire tripartite face/color/place system of primates migrated onto the ventral surface in humans over the course of evolution. National Institutes of Health (U.S.) (Grant EY13455) National Institutes of Health (U.S.) (Grant EY023322) National Institutes of Health (U.S.) (Grant 5T32GM007484-38) National Science Foundation (U.S.) (STC Award CCF-1231216) National Science Foundation (U.S.) (Grant 1353571) National Science Foundation (U.S.). Graduate Research Fellowship 2016-05-12T00:46:43Z 2016-05-12T00:46:43Z 2016-02 2015-10 Article http://purl.org/eprint/type/JournalArticle 0270-6474 1529-2401 http://hdl.handle.net/1721.1/102459 Lafer-Sousa, R., B. R. Conway, and N. G. Kanwisher. “Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques.” Journal of Neuroscience 36, no. 5 (February 3, 2016): 1682–97. https://orcid.org/0000-0002-4514-0299 https://orcid.org/0000-0003-3853-7885 en_US http://dx.doi.org/10.1523/jneurosci.3164-15.2016 Journal of Neuroscience Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/ application/pdf Society for Neuroscience Journal of Neuroscience |
| spellingShingle | Lafer-Sousa, Rosa Conway, Bevil Kanwisher, Nancy Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques |
| title | Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques |
| title_full | Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques |
| title_fullStr | Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques |
| title_full_unstemmed | Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques |
| title_short | Color-Biased Regions of the Ventral Visual Pathway Lie between Face- and Place-Selective Regions in Humans, as in Macaques |
| title_sort | color biased regions of the ventral visual pathway lie between face and place selective regions in humans as in macaques |
| url | http://hdl.handle.net/1721.1/102459 https://orcid.org/0000-0002-4514-0299 https://orcid.org/0000-0003-3853-7885 |
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