Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice

Disruptions in circadian rhythms and dopaminergic activity are involved in the pathophysiology of bipolar disorder, though their interaction remains unclear. Moreover, a lack of animal models that display spontaneous cycling between mood states has hindered our mechanistic understanding of mood swit...

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Bibliographic Details
Main Authors: Sidor, M. M., Spencer, S. M., Dzirasa, K., Parekh, P. K., Tye, Kay, Warden, M. R., Arey, R. N., Enwright, J. F., Jacobsen, J. P. R., Kumar, S., Remillard, E. M., Caron, M. G., Deisseroth, K., McClung, C. A.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/102523

Internet

http://hdl.handle.net/1721.1/102523

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