PTEN knockdown alters dendritic spine/protrusion morphology, not density

PTEN knockdown alters dendritic spine/protrusion morphology, not density

Mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) are implicated in neuropsychiatric disorders including autism. Previous studies report that PTEN knockdown in neurons in vivo leads to increased spine density and synaptic activity. To better characterize synaptic changes in...

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Bibliographic Details
Main Authors: Haws, Michael E., Jaramillo, Thomas C., Espinosa, Felipe, J. Widman, Allie, Stuber, Garret D., Sparta, Dennis R., Russo, Scott J., Parada, Luis F., Stavarache, Mihaela, Kaplitt, Michael, Bonci, Antonello, Powell, Craig M., Tye, Kay
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Wiley Blackwell 2016
Online Access:http://hdl.handle.net/1721.1/102670

Internet

http://hdl.handle.net/1721.1/102670

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