Optical control of mammalian endogenous transcription and epigenetic states

Optical control of mammalian endogenous transcription and epigenetic states

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The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene e...

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Bibliographic Details
Main Authors: Konermann, Silvana M., Brigham, Mark D., Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Church, George M., Zhang, Feng
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/102696
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0001-7915-1685
https://orcid.org/0000-0002-2639-9879
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