A single-molecule characterization of p53 search on DNA
The tumor suppressor p53 slides along DNA while searching for its cognate site. Central to this process is the basic C-terminal domain, whose regulatory role and its coordination with the core DNA-binding domain is highly debated. Here we use single-molecule techniques to characterize the search pro...
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2016
|
| Online Access: | http://hdl.handle.net/1721.1/102871 https://orcid.org/0000-0002-0785-5410 |