Plug-and-play microvalve and micropump for rapid integration with microfluidic chips

This paper reports design, fabrication, and characterization of an air-actuated microvalve and a micropump made of thermoplastic materials. The bonding process was carried out by thermal fusion process with no particular surface treatment. The developed microvalve was used as a reversible switch for...

Full description

Bibliographic Details
Main Authors: Mousavi Shaegh, Seyed Ali, Wang, Zhenfeng, Ng, Sum Huan, Wu, Ruige, Nguyen, Huu Tuan, Chan, Leon Cong Zhi, Toh, Alicia Guek Geok, Wang, Zhiping
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Springer Berlin Heidelberg 2016
Online Access:http://hdl.handle.net/1721.1/103131
_version_ 1826191985156816896
author Mousavi Shaegh, Seyed Ali
Wang, Zhenfeng
Ng, Sum Huan
Wu, Ruige
Nguyen, Huu Tuan
Chan, Leon Cong Zhi
Toh, Alicia Guek Geok
Wang, Zhiping
author2 Harvard University--MIT Division of Health Sciences and Technology
author_facet Harvard University--MIT Division of Health Sciences and Technology
Mousavi Shaegh, Seyed Ali
Wang, Zhenfeng
Ng, Sum Huan
Wu, Ruige
Nguyen, Huu Tuan
Chan, Leon Cong Zhi
Toh, Alicia Guek Geok
Wang, Zhiping
author_sort Mousavi Shaegh, Seyed Ali
collection MIT
description This paper reports design, fabrication, and characterization of an air-actuated microvalve and a micropump made of thermoplastic materials. The bonding process was carried out by thermal fusion process with no particular surface treatment. The developed microvalve was used as a reversible switch for controlling both liquid flow and electrical field. Bonding strength of the fabricated microvalves could withstand liquid and air pressures of up to 600 kPa with no burst failure. The micropump made of three connected microvalves, actuated by compressed air, could generate a liquid flow rate of up to 85 µl/min. The proposed microvalve and micropump can be used as pre-fabricated off-the-shelf microfluidic functional elements for easy and rapid integration with thermoplastic microfluidic circuitries in a plug-and-play arrangement.
first_indexed 2024-09-23T09:04:24Z
format Article
id mit-1721.1/103131
institution Massachusetts Institute of Technology
language English
last_indexed 2024-09-23T09:04:24Z
publishDate 2016
publisher Springer Berlin Heidelberg
record_format dspace
spelling mit-1721.1/1031312022-09-30T13:16:06Z Plug-and-play microvalve and micropump for rapid integration with microfluidic chips Mousavi Shaegh, Seyed Ali Wang, Zhenfeng Ng, Sum Huan Wu, Ruige Nguyen, Huu Tuan Chan, Leon Cong Zhi Toh, Alicia Guek Geok Wang, Zhiping Harvard University--MIT Division of Health Sciences and Technology Mousavi Shaegh, Seyed Ali This paper reports design, fabrication, and characterization of an air-actuated microvalve and a micropump made of thermoplastic materials. The bonding process was carried out by thermal fusion process with no particular surface treatment. The developed microvalve was used as a reversible switch for controlling both liquid flow and electrical field. Bonding strength of the fabricated microvalves could withstand liquid and air pressures of up to 600 kPa with no burst failure. The micropump made of three connected microvalves, actuated by compressed air, could generate a liquid flow rate of up to 85 µl/min. The proposed microvalve and micropump can be used as pre-fabricated off-the-shelf microfluidic functional elements for easy and rapid integration with thermoplastic microfluidic circuitries in a plug-and-play arrangement. 2016-06-16T20:45:19Z 2016-06-16T20:45:19Z 2015-04 2015-01 2016-05-23T12:11:52Z Article http://purl.org/eprint/type/JournalArticle 1613-4982 1613-4990 http://hdl.handle.net/1721.1/103131 Shaegh, Seyed Ali Mousavi, Zhenfeng Wang, Sum Huan Ng, Ruige Wu, Huu Tuan Nguyen, Leon Cong Zhi Chan, Alicia Guek Geok Toh, and Zhiping Wang. “Plug-and-Play Microvalve and Micropump for Rapid Integration with Microfluidic Chips.” Microfluid Nanofluid 19, no. 3 (April 22, 2015): 557–564. en http://dx.doi.org/10.1007/s10404-015-1582-4 Microfluidics and Nanofluidics Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. Springer-Verlag Berlin Heidelberg application/pdf Springer Berlin Heidelberg Springer Berlin Heidelberg
spellingShingle Mousavi Shaegh, Seyed Ali
Wang, Zhenfeng
Ng, Sum Huan
Wu, Ruige
Nguyen, Huu Tuan
Chan, Leon Cong Zhi
Toh, Alicia Guek Geok
Wang, Zhiping
Plug-and-play microvalve and micropump for rapid integration with microfluidic chips
title Plug-and-play microvalve and micropump for rapid integration with microfluidic chips
title_full Plug-and-play microvalve and micropump for rapid integration with microfluidic chips
title_fullStr Plug-and-play microvalve and micropump for rapid integration with microfluidic chips
title_full_unstemmed Plug-and-play microvalve and micropump for rapid integration with microfluidic chips
title_short Plug-and-play microvalve and micropump for rapid integration with microfluidic chips
title_sort plug and play microvalve and micropump for rapid integration with microfluidic chips
url http://hdl.handle.net/1721.1/103131
work_keys_str_mv AT mousavishaeghseyedali plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT wangzhenfeng plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT ngsumhuan plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT wuruige plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT nguyenhuutuan plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT chanleoncongzhi plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT tohaliciaguekgeok plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips
AT wangzhiping plugandplaymicrovalveandmicropumpforrapidintegrationwithmicrofluidicchips