A Computational Model of Inhibition of HIV-1 by Interferon-Alpha
Type 1 interferons such as interferon-alpha (IFNα) inhibit replication of Human immunodeficiency virus (HIV-1) by upregulating the expression of genes that interfere with specific steps in the viral life cycle. This pathway thus represents a potential target for immune-based therapies that can alter...
Main Authors: | Browne, Edward P., Letham, Benjamin, Rudin, Cynthia |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2016
|
Online Access: | http://hdl.handle.net/1721.1/103599 |
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