Low-Transition-Temperature Mixtures (LTTMs) for Dissolving Proteins and for Drug Formulation

Several diverse proteins are found to readily dissolve in neat low-transition-temperature mixtures (LTTMs). They undergo no irreversible denaturation in such unusual solvents, and the resistance of hen egg-white lysozyme against thermoinactivation in LTTMs is greater than in aqueous solution at extr...

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Bibliographic Details
Main Authors: Su, Erzheng, Klibanov, Alexander M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer US 2016
Online Access:http://hdl.handle.net/1721.1/103634
https://orcid.org/0000-0003-3830-714X

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