Low-Transition-Temperature Mixtures (LTTMs) for Dissolving Proteins and for Drug Formulation
Several diverse proteins are found to readily dissolve in neat low-transition-temperature mixtures (LTTMs). They undergo no irreversible denaturation in such unusual solvents, and the resistance of hen egg-white lysozyme against thermoinactivation in LTTMs is greater than in aqueous solution at extr...
Main Authors: | Su, Erzheng, Klibanov, Alexander M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Springer US
2016
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Online Access: | http://hdl.handle.net/1721.1/103634 https://orcid.org/0000-0003-3830-714X |
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