Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects

Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects

Pharmacological concentrations of small molecule natural products, such as ascorbic acid, have exhibited distinct cell killing outcomes between cancer and normal cells whereby cancer cells undergo apoptosis or necrosis while normal cells are not adversely affected. Here, we develop a mathematical mo...

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Bibliographic Details
Main Authors: Molavian, Hamid R., Goldman, Aaron, Phipps, Colin J., Kohandel, Mohammad, Wouters, Bradly G., Sengupta, Shiladitya, Sivaloganathan, Sivabal
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Springer Nature 2016
Online Access:http://hdl.handle.net/1721.1/103862

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