A Central Role for mTOR in Lipid Homeostasis
The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic and physiological processes, including lipid metabolism. We explore recent findings on the role of mTOR in lipid homeostasis, with an emphasis on recent findings from in vivo models regarding the role o...
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| Format: | Article |
| Language: | en_US |
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Elsevier
2016
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| Online Access: | http://hdl.handle.net/1721.1/103878 https://orcid.org/0000-0002-0079-4467 https://orcid.org/0000-0002-1446-7256 |
| _version_ | 1826205816954290176 |
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| author | Lamming, Dudley W. Sabatini, David M. Lamming, Dudley W. Sabatini, David |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Lamming, Dudley W. Sabatini, David M. Lamming, Dudley W. Sabatini, David |
| author_sort | Lamming, Dudley W. |
| collection | MIT |
| description | The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic and physiological processes, including lipid metabolism. We explore recent findings on the role of mTOR in lipid homeostasis, with an emphasis on recent findings from in vivo models regarding the role of mTORC2 in lipolysis, lipogenesis, and adipogenesis. |
| first_indexed | 2024-09-23T13:19:34Z |
| format | Article |
| id | mit-1721.1/103878 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:19:34Z |
| publishDate | 2016 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/1038782022-10-01T14:32:50Z A Central Role for mTOR in Lipid Homeostasis Lamming, Dudley W. Sabatini, David M. Lamming, Dudley W. Sabatini, David Massachusetts Institute of Technology. Department of Biology Whitehead Institute for Biomedical Research Koch Institute for Integrative Cancer Research at MIT Lamming, Dudley W. Sabatini, David M. The mechanistic target of rapamycin (mTOR) signaling pathway regulates many fundamental metabolic and physiological processes, including lipid metabolism. We explore recent findings on the role of mTOR in lipid homeostasis, with an emphasis on recent findings from in vivo models regarding the role of mTORC2 in lipolysis, lipogenesis, and adipogenesis. Howard Hughes Medical Institute (Investigator) National Institutes of Health (U.S.) (K99/R00 award from the NIH/NIA (AG041765)) 2016-08-10T15:40:24Z 2016-08-10T15:40:24Z 2013-08 Article http://purl.org/eprint/type/JournalArticle 15504131 http://hdl.handle.net/1721.1/103878 Lamming, Dudley W., and David M. Sabatini. “A Central Role for mTOR in Lipid Homeostasis.” Cell Metabolism 18, no. 4 (October 2013): 465-469. https://orcid.org/0000-0002-0079-4467 https://orcid.org/0000-0002-1446-7256 en_US http://dx.doi.org/10.1016/j.cmet.2013.08.002 Cell Metabolism Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier PMC |
| spellingShingle | Lamming, Dudley W. Sabatini, David M. Lamming, Dudley W. Sabatini, David A Central Role for mTOR in Lipid Homeostasis |
| title | A Central Role for mTOR in Lipid Homeostasis |
| title_full | A Central Role for mTOR in Lipid Homeostasis |
| title_fullStr | A Central Role for mTOR in Lipid Homeostasis |
| title_full_unstemmed | A Central Role for mTOR in Lipid Homeostasis |
| title_short | A Central Role for mTOR in Lipid Homeostasis |
| title_sort | central role for mtor in lipid homeostasis |
| url | http://hdl.handle.net/1721.1/103878 https://orcid.org/0000-0002-0079-4467 https://orcid.org/0000-0002-1446-7256 |
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