Chemistry with an Artificial Primer of Polyhydroxybutyrate Synthase Suggests a Mechanism for Chain Termination
Polyhydroxybutyrate (PHB) synthases (PhaCs) catalyze the conversion of 3-(R)-hydroxybutyryl CoA (HBCoA) to PHB, which is deposited as granules in the cytoplasm of microorganisms. The class I PhaC from Caulobacter crescentus (PhaC[subscript Cc]) is a highly soluble protein with a turnover number of 7...
Main Authors: | Stubbe, JoAnne, Buckley, Rachael M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2016
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Online Access: | http://hdl.handle.net/1721.1/103958 https://orcid.org/0000-0001-8076-4489 |
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