Smart nanosystems: Bio-inspired technologies that interact with the host environment

Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the...

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Bibliographic Details
Main Authors: Kwon, Ester, Lo, Justin H., Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2016
Online Access:http://hdl.handle.net/1721.1/103977
https://orcid.org/0000-0001-5981-2589
https://orcid.org/0000-0002-1293-2097
https://orcid.org/0000-0002-6335-9681
Description
Summary:Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health.