Smart nanosystems: Bio-inspired technologies that interact with the host environment
Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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National Academy of Sciences (U.S.)
2016
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| Online Access: | http://hdl.handle.net/1721.1/103977 https://orcid.org/0000-0001-5981-2589 https://orcid.org/0000-0002-1293-2097 https://orcid.org/0000-0002-6335-9681 |
| _version_ | 1826201612860784640 |
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| author | Kwon, Ester Lo, Justin H. Bhatia, Sangeeta N |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Kwon, Ester Lo, Justin H. Bhatia, Sangeeta N |
| author_sort | Kwon, Ester |
| collection | MIT |
| description | Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health. |
| first_indexed | 2024-09-23T11:54:06Z |
| format | Article |
| id | mit-1721.1/103977 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:54:06Z |
| publishDate | 2016 |
| publisher | National Academy of Sciences (U.S.) |
| record_format | dspace |
| spelling | mit-1721.1/1039772022-09-27T22:44:22Z Smart nanosystems: Bio-inspired technologies that interact with the host environment Kwon, Ester Lo, Justin H. Bhatia, Sangeeta N Massachusetts Institute of Technology. Institute for Medical Engineering & Science Koch Institute for Integrative Cancer Research at MIT Kwon, Ester Lo, Justin H. Bhatia, Sangeeta N. Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: (i) those that sense the host environment and respond and (ii) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health. National Cancer Institute (U.S.) (Koch Institute Support Grant P30-CA14051) National Institute of Environmental Health Sciences (Core Center Grant P30-ES002109) Amar G. Bose (research grant) United States. Defense Advanced Research Projects Agency (Cooperative Agreement HR0011-13-2-0017) 2016-08-25T15:38:19Z 2016-08-25T15:38:19Z 2015-11 2015-06 Article http://purl.org/eprint/type/JournalArticle 0027-8424 1091-6490 http://hdl.handle.net/1721.1/103977 Kwon, Ester J., Justin H. Lo, and Sangeeta N. Bhatia. “Smart Nanosystems: Bio-Inspired Technologies That Interact with the Host Environment.” Proc Natl Acad Sci USA 112, no. 47 (November 23, 2015): 14460–14466. © 2016 National Academy of Sciences. 26598694 https://orcid.org/0000-0001-5981-2589 https://orcid.org/0000-0002-1293-2097 https://orcid.org/0000-0002-6335-9681 en_US http://dx.doi.org/10.1073/pnas.1508522112 Proceedings of the National Academy of Sciences Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf National Academy of Sciences (U.S.) National Academy of Sciences (U.S.) |
| spellingShingle | Kwon, Ester Lo, Justin H. Bhatia, Sangeeta N Smart nanosystems: Bio-inspired technologies that interact with the host environment |
| title | Smart nanosystems: Bio-inspired technologies that interact with the host environment |
| title_full | Smart nanosystems: Bio-inspired technologies that interact with the host environment |
| title_fullStr | Smart nanosystems: Bio-inspired technologies that interact with the host environment |
| title_full_unstemmed | Smart nanosystems: Bio-inspired technologies that interact with the host environment |
| title_short | Smart nanosystems: Bio-inspired technologies that interact with the host environment |
| title_sort | smart nanosystems bio inspired technologies that interact with the host environment |
| url | http://hdl.handle.net/1721.1/103977 https://orcid.org/0000-0001-5981-2589 https://orcid.org/0000-0002-1293-2097 https://orcid.org/0000-0002-6335-9681 |
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