Biomarkers and diagnostic tools for detection of Helicobacter pylori
Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and...
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Berlin Heidelberg
2016
|
| Online Access: | http://hdl.handle.net/1721.1/104361 |
| _version_ | 1811079559990214656 |
|---|---|
| author | Khalilpour, Akbar Kazemzadeh-Narbat, Mehdi Tamayol, Ali Oklu, Rahmi Khademhosseini, Ali |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Khalilpour, Akbar Kazemzadeh-Narbat, Mehdi Tamayol, Ali Oklu, Rahmi Khademhosseini, Ali |
| author_sort | Khalilpour, Akbar |
| collection | MIT |
| description | Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms. |
| first_indexed | 2024-09-23T11:16:57Z |
| format | Article |
| id | mit-1721.1/104361 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:16:57Z |
| publishDate | 2016 |
| publisher | Springer Berlin Heidelberg |
| record_format | dspace |
| spelling | mit-1721.1/1043612022-10-01T02:35:42Z Biomarkers and diagnostic tools for detection of Helicobacter pylori Khalilpour, Akbar Kazemzadeh-Narbat, Mehdi Tamayol, Ali Oklu, Rahmi Khademhosseini, Ali Massachusetts Institute of Technology. Institute for Medical Engineering & Science Harvard University--MIT Division of Health Sciences and Technology Khalilpour, Akbar Kazemzadeh-Narbat, Mehdi Tamayol, Ali Khademhosseini, Alireza Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms. 2016-09-21T19:23:42Z 2017-03-01T16:14:49Z 2016-04 2016-03 2016-08-18T15:24:33Z Article http://purl.org/eprint/type/JournalArticle 0175-7598 1432-0614 http://hdl.handle.net/1721.1/104361 Khalilpour, Akbar, Mehdi Kazemzadeh-Narbat, Ali Tamayol, Rahmi Oklu, and Ali Khademhosseini. “Biomarkers and Diagnostic Tools for Detection of Helicobacter Pylori.” Applied Microbiology and Biotechnology 100, no. 11 (April 15, 2016): 4723-4734. en http://dx.doi.org/10.1007/s00253-016-7495-7 Applied Microbiology and Biotechnology Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. Springer-Verlag Berlin Heidelberg application/pdf Springer Berlin Heidelberg Springer Berlin Heidelberg |
| spellingShingle | Khalilpour, Akbar Kazemzadeh-Narbat, Mehdi Tamayol, Ali Oklu, Rahmi Khademhosseini, Ali Biomarkers and diagnostic tools for detection of Helicobacter pylori |
| title | Biomarkers and diagnostic tools for detection of Helicobacter pylori |
| title_full | Biomarkers and diagnostic tools for detection of Helicobacter pylori |
| title_fullStr | Biomarkers and diagnostic tools for detection of Helicobacter pylori |
| title_full_unstemmed | Biomarkers and diagnostic tools for detection of Helicobacter pylori |
| title_short | Biomarkers and diagnostic tools for detection of Helicobacter pylori |
| title_sort | biomarkers and diagnostic tools for detection of helicobacter pylori |
| url | http://hdl.handle.net/1721.1/104361 |
| work_keys_str_mv | AT khalilpourakbar biomarkersanddiagnostictoolsfordetectionofhelicobacterpylori AT kazemzadehnarbatmehdi biomarkersanddiagnostictoolsfordetectionofhelicobacterpylori AT tamayolali biomarkersanddiagnostictoolsfordetectionofhelicobacterpylori AT oklurahmi biomarkersanddiagnostictoolsfordetectionofhelicobacterpylori AT khademhosseiniali biomarkersanddiagnostictoolsfordetectionofhelicobacterpylori |