Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis)
A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8- and 16-fold difference, respectively, in their titers....
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Springer Vienna
2016
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| Online Access: | http://hdl.handle.net/1721.1/104367 https://orcid.org/0000-0002-6747-7765 |
| _version_ | 1826209668645519360 |
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| author | Bui, Vuong Nghia Mizutani, Tetsuya Nguyen, Tung Hoang Trinh, Dai Quang Awad, Sanaa S. A. Minoungou, Germaine L. Yamamoto, Yu Nakamura, Kikuyasu Saito, Keisuke Watanabe, Yukiko Runstadler, Jonathan Huettmann, Falk Ogawa, Haruko Imai, Kunitoshi |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Bui, Vuong Nghia Mizutani, Tetsuya Nguyen, Tung Hoang Trinh, Dai Quang Awad, Sanaa S. A. Minoungou, Germaine L. Yamamoto, Yu Nakamura, Kikuyasu Saito, Keisuke Watanabe, Yukiko Runstadler, Jonathan Huettmann, Falk Ogawa, Haruko Imai, Kunitoshi |
| author_sort | Bui, Vuong Nghia |
| collection | MIT |
| description | A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8- and 16-fold difference, respectively, in their titers. The full genome sequence of 8KS0813 showed 98.6 % nucleotide sequence identity to that of APMV-6/duck/Italy/4524-2/07, which has been reported to belong to an APMV-6 subgroup, and showed less similarity to that of the prototype strain (70.6 % similarity). The growth of 8KS0813 and the prototype strain in four different cell cultures was greatly enhanced by adding trypsin. Interestingly, this virus induced syncytia only in Vero cells. 8KS0813 was identified as APMV-6/red-necked stint/Japan/8KS0813/08, but it is antigenically and genetically distinguishable from the prototype strain, suggesting that variant APMV-6 is circulating in migratory birds. |
| first_indexed | 2024-09-23T14:26:33Z |
| format | Article |
| id | mit-1721.1/104367 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T14:26:33Z |
| publishDate | 2016 |
| publisher | Springer Vienna |
| record_format | dspace |
| spelling | mit-1721.1/1043672022-09-29T09:28:39Z Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) Bui, Vuong Nghia Mizutani, Tetsuya Nguyen, Tung Hoang Trinh, Dai Quang Awad, Sanaa S. A. Minoungou, Germaine L. Yamamoto, Yu Nakamura, Kikuyasu Saito, Keisuke Watanabe, Yukiko Runstadler, Jonathan Huettmann, Falk Ogawa, Haruko Imai, Kunitoshi Massachusetts Institute of Technology. Department of Biological Engineering Runstadler, Jonathan A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8- and 16-fold difference, respectively, in their titers. The full genome sequence of 8KS0813 showed 98.6 % nucleotide sequence identity to that of APMV-6/duck/Italy/4524-2/07, which has been reported to belong to an APMV-6 subgroup, and showed less similarity to that of the prototype strain (70.6 % similarity). The growth of 8KS0813 and the prototype strain in four different cell cultures was greatly enhanced by adding trypsin. Interestingly, this virus induced syncytia only in Vero cells. 8KS0813 was identified as APMV-6/red-necked stint/Japan/8KS0813/08, but it is antigenically and genetically distinguishable from the prototype strain, suggesting that variant APMV-6 is circulating in migratory birds. Program of Founding Research Centers for Emerging and Reemerging Infectious Diseases Japan. Ministry of Education, Culture, Sports, Science and Technology (Grant-in-Aid for Exploratory Research (19659115)) National Institute of Allergy and Infectious Diseases (U.S.) (NIAID contracts HHSN266200700009C and HHSN266200700007C) 2016-09-22T17:56:58Z 2016-09-22T17:56:58Z 2014-07 2014-01 2016-08-18T15:21:35Z Article http://purl.org/eprint/type/JournalArticle 0304-8608 1432-8798 http://hdl.handle.net/1721.1/104367 Kitajima, Masaaki et al. “Occurrence and Genetic Diversity of Human Cosavirus in Influent and Effluent of Wastewater Treatment Plants in Arizona, United States.” Archives of Virology 160.7 (2015): 1775–1779. https://orcid.org/0000-0002-6747-7765 en http://dx.doi.org/10.1007/s00705-014-2162-8 Archives of Virology Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ Springer-Verlag Wien application/pdf Springer Vienna Springer Vienna |
| spellingShingle | Bui, Vuong Nghia Mizutani, Tetsuya Nguyen, Tung Hoang Trinh, Dai Quang Awad, Sanaa S. A. Minoungou, Germaine L. Yamamoto, Yu Nakamura, Kikuyasu Saito, Keisuke Watanabe, Yukiko Runstadler, Jonathan Huettmann, Falk Ogawa, Haruko Imai, Kunitoshi Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) |
| title | Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) |
| title_full | Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) |
| title_fullStr | Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) |
| title_full_unstemmed | Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) |
| title_short | Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis) |
| title_sort | characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird the red necked stint calidris ruficollis |
| url | http://hdl.handle.net/1721.1/104367 https://orcid.org/0000-0002-6747-7765 |
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