NURBS modeling and structural shape optimization of cardiovascular stents
Cardiovascular stents have been used since the 1990s to treat atherosclerosis, one of leading causes of death in the western world, and structural optimization has led to significant improvements in stent performance. Much of the potential variation in stent geometry, however, has remained unconside...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
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Springer Berlin Heidelberg
2016
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| Online Access: | http://hdl.handle.net/1721.1/104952 |
| _version_ | 1811082070391259136 |
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| author | Kelliher, Denis Robinson, James C. Campbell, John S. Clune, Rory P. |
| author2 | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Kelliher, Denis Robinson, James C. Campbell, John S. Clune, Rory P. |
| author_sort | Kelliher, Denis |
| collection | MIT |
| description | Cardiovascular stents have been used since the 1990s to treat atherosclerosis, one of leading causes of death in the western world, and structural optimization has led to significant improvements in stent performance. Much of the potential variation in stent geometry, however, has remained unconsidered. This paper presents a non-uniform rational basis spline (NURBS) parameterization of a stent, the inclusion of structural fatigue resistance as a design consideration, and the results of a design optimization based on response surface techniques. Results show the feasibility and merits of the NURBS approach, which models a much broader range of shapes than was previously possible. Multi-objective optimization produces a range of geometrically diverse Pareto-optimal designs; these can be used to develop future clinical design guides, accounting for the variation observed across patients. We conclude by motivating future work with increasingly complex physical modeling and optimization capabilities. |
| first_indexed | 2024-09-23T11:57:05Z |
| format | Article |
| id | mit-1721.1/104952 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:57:05Z |
| publishDate | 2016 |
| publisher | Springer Berlin Heidelberg |
| record_format | dspace |
| spelling | mit-1721.1/1049522022-09-27T23:04:16Z NURBS modeling and structural shape optimization of cardiovascular stents Kelliher, Denis Robinson, James C. Campbell, John S. Clune, Rory P. Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Clune, Rory P. Cardiovascular stents have been used since the 1990s to treat atherosclerosis, one of leading causes of death in the western world, and structural optimization has led to significant improvements in stent performance. Much of the potential variation in stent geometry, however, has remained unconsidered. This paper presents a non-uniform rational basis spline (NURBS) parameterization of a stent, the inclusion of structural fatigue resistance as a design consideration, and the results of a design optimization based on response surface techniques. Results show the feasibility and merits of the NURBS approach, which models a much broader range of shapes than was previously possible. Multi-objective optimization produces a range of geometrically diverse Pareto-optimal designs; these can be used to develop future clinical design guides, accounting for the variation observed across patients. We conclude by motivating future work with increasingly complex physical modeling and optimization capabilities. 2016-10-24T18:56:51Z 2016-10-24T18:56:51Z 2014-01 2013-09 2016-08-18T15:23:34Z Article http://purl.org/eprint/type/JournalArticle 1615-147X 1615-1488 http://hdl.handle.net/1721.1/104952 Clune, Rory et al. “NURBS Modeling and Structural Shape Optimization of Cardiovascular Stents.” Structural and Multidisciplinary Optimization 50.1 (2014): 159–168. en http://dx.doi.org/10.1007/s00158-013-1038-y Structural and Multidisciplinary Optimization Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. Springer-Verlag Berlin Heidelberg application/pdf Springer Berlin Heidelberg Springer Berlin Heidelberg |
| spellingShingle | Kelliher, Denis Robinson, James C. Campbell, John S. Clune, Rory P. NURBS modeling and structural shape optimization of cardiovascular stents |
| title | NURBS modeling and structural shape optimization of cardiovascular stents |
| title_full | NURBS modeling and structural shape optimization of cardiovascular stents |
| title_fullStr | NURBS modeling and structural shape optimization of cardiovascular stents |
| title_full_unstemmed | NURBS modeling and structural shape optimization of cardiovascular stents |
| title_short | NURBS modeling and structural shape optimization of cardiovascular stents |
| title_sort | nurbs modeling and structural shape optimization of cardiovascular stents |
| url | http://hdl.handle.net/1721.1/104952 |
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