Temporal Registration in In-Utero Volumetric MRI Time Series

We present a robust method to correct for motion and deformations in in-utero volumetric MRI time series. Spatio-temporal analysis of dynamic MRI requires robust alignment across time in the presence of substantial and unpredictable motion. We make a Markov assumption on the nature of deformations t...

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Bibliographic Details
Main Authors: Grant, P. Ellen, Liao, Ruizhi, Abaci Turk, Esra, Zhang, Miaomiao, Luo, Jie, Adalsteinsson, Elfar, Golland, Polina
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: MICCAI Society 2016
Online Access:http://hdl.handle.net/1721.1/105124
https://orcid.org/0000-0001-6761-921X
https://orcid.org/0000-0003-0246-8793
https://orcid.org/0000-0002-0543-4778
https://orcid.org/0000-0002-7637-2914
https://orcid.org/0000-0003-2516-731X
Description
Summary:We present a robust method to correct for motion and deformations in in-utero volumetric MRI time series. Spatio-temporal analysis of dynamic MRI requires robust alignment across time in the presence of substantial and unpredictable motion. We make a Markov assumption on the nature of deformations to take advantage of the temporal structure in the image data. Forward message passing in the corresponding hidden Markov model (HMM) yields an estimation algorithm that only has to account for relatively small motion between consecutive frames. We demonstrate the utility of the temporal model by showing that its use improves the accuracy of the segmentation propagation through temporal registration. Our results suggest that the proposed model captures accurately the temporal dynamics of deformations in in-utero MRI time series.