Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution
The Asian tiger mosquito, Aedes albopictus, is a highly successful invasive species that transmits a number of human viral diseases, including dengue and Chikungunya fevers. This species has a large genome with significant population-based size variation. The complete genome sequence was determined...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | en_US |
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National Academy of Sciences (U.S.)
2016
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| Online Access: | http://hdl.handle.net/1721.1/105183 |
| _version_ | 1811079248440459264 |
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| author | Chen, Xiao-Guang Jiang, Xuanting Gu, Jinbao Xu, Meng Wu, Yang Deng, Yuhua Zhang, Chi Bonizzoni, Mariangela Dermauw, Wannes Vontas, John Armbruster, Peter Huang, Xin Yang, Yulan Zhang, Hao He, Weiming Peng, Hongjuan Liu, Yongfeng Wu, Kun Chen, Jiahua Lirakis, Manolis Topalis, Pantelis Van Leeuwen, Thomas Hall, Andrew Brantley Jiang, Xiaofang Thorpe, Chevon Mueller, Rachel Lockridge Sun, Cheng Yan, Guiyun Tu, Zhijian Jake Fang, Xiaodong James, Anthony A. Waterhouse, Robert |
| author2 | Broad Institute of MIT and Harvard |
| author_facet | Broad Institute of MIT and Harvard Chen, Xiao-Guang Jiang, Xuanting Gu, Jinbao Xu, Meng Wu, Yang Deng, Yuhua Zhang, Chi Bonizzoni, Mariangela Dermauw, Wannes Vontas, John Armbruster, Peter Huang, Xin Yang, Yulan Zhang, Hao He, Weiming Peng, Hongjuan Liu, Yongfeng Wu, Kun Chen, Jiahua Lirakis, Manolis Topalis, Pantelis Van Leeuwen, Thomas Hall, Andrew Brantley Jiang, Xiaofang Thorpe, Chevon Mueller, Rachel Lockridge Sun, Cheng Yan, Guiyun Tu, Zhijian Jake Fang, Xiaodong James, Anthony A. Waterhouse, Robert |
| author_sort | Chen, Xiao-Guang |
| collection | MIT |
| description | The Asian tiger mosquito, Aedes albopictus, is a highly successful invasive species that transmits a number of human viral diseases, including dengue and Chikungunya fevers. This species has a large genome with significant population-based size variation. The complete genome sequence was determined for the Foshan strain, an established laboratory colony derived from wild mosquitoes from southeastern China, a region within the historical range of the origin of the species. The genome comprises 1,967 Mb, the largest mosquito genome sequenced to date, and its size results principally from an abundance of repetitive DNA classes. In addition, expansions of the numbers of members in gene families involved in insecticide-resistance mechanisms, diapause, sex determination, immunity, and olfaction also contribute to the larger size. Portions of integrated flavivirus-like genomes support a shared evolutionary history of association of these viruses with their vector. The large genome repertory may contribute to the adaptability and success of Ae. albopictus as an invasive species. |
| first_indexed | 2024-09-23T11:12:12Z |
| format | Article |
| id | mit-1721.1/105183 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:12:12Z |
| publishDate | 2016 |
| publisher | National Academy of Sciences (U.S.) |
| record_format | dspace |
| spelling | mit-1721.1/1051832022-09-27T17:49:36Z Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution Chen, Xiao-Guang Jiang, Xuanting Gu, Jinbao Xu, Meng Wu, Yang Deng, Yuhua Zhang, Chi Bonizzoni, Mariangela Dermauw, Wannes Vontas, John Armbruster, Peter Huang, Xin Yang, Yulan Zhang, Hao He, Weiming Peng, Hongjuan Liu, Yongfeng Wu, Kun Chen, Jiahua Lirakis, Manolis Topalis, Pantelis Van Leeuwen, Thomas Hall, Andrew Brantley Jiang, Xiaofang Thorpe, Chevon Mueller, Rachel Lockridge Sun, Cheng Yan, Guiyun Tu, Zhijian Jake Fang, Xiaodong James, Anthony A. Waterhouse, Robert Broad Institute of MIT and Harvard Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Waterhouse, Robert The Asian tiger mosquito, Aedes albopictus, is a highly successful invasive species that transmits a number of human viral diseases, including dengue and Chikungunya fevers. This species has a large genome with significant population-based size variation. The complete genome sequence was determined for the Foshan strain, an established laboratory colony derived from wild mosquitoes from southeastern China, a region within the historical range of the origin of the species. The genome comprises 1,967 Mb, the largest mosquito genome sequenced to date, and its size results principally from an abundance of repetitive DNA classes. In addition, expansions of the numbers of members in gene families involved in insecticide-resistance mechanisms, diapause, sex determination, immunity, and olfaction also contribute to the larger size. Portions of integrated flavivirus-like genomes support a shared evolutionary history of association of these viruses with their vector. The large genome repertory may contribute to the adaptability and success of Ae. albopictus as an invasive species. Marie Curie International Fellowship (Grant PIOFGA-2011-303312) 2016-11-03T18:49:24Z 2016-11-03T18:49:24Z 2015-11 2015-08 Article http://purl.org/eprint/type/JournalArticle 0027-8424 1091-6490 http://hdl.handle.net/1721.1/105183 Chen, Xiao-Guang et al. “Genome Sequence of the Asian Tiger Mosquito, Aedes Albopictus , Reveals Insights into Its Biology, Genetics, and Evolution.” Proceedings of the National Academy of Sciences 112.44 (2015): E5907–E5915. en_US http://dx.doi.org/10.1073/pnas.1516410112 Proceedings of the National Academy of Sciences of the United States of America Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf National Academy of Sciences (U.S.) PNAS |
| spellingShingle | Chen, Xiao-Guang Jiang, Xuanting Gu, Jinbao Xu, Meng Wu, Yang Deng, Yuhua Zhang, Chi Bonizzoni, Mariangela Dermauw, Wannes Vontas, John Armbruster, Peter Huang, Xin Yang, Yulan Zhang, Hao He, Weiming Peng, Hongjuan Liu, Yongfeng Wu, Kun Chen, Jiahua Lirakis, Manolis Topalis, Pantelis Van Leeuwen, Thomas Hall, Andrew Brantley Jiang, Xiaofang Thorpe, Chevon Mueller, Rachel Lockridge Sun, Cheng Yan, Guiyun Tu, Zhijian Jake Fang, Xiaodong James, Anthony A. Waterhouse, Robert Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution |
| title | Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution |
| title_full | Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution |
| title_fullStr | Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution |
| title_full_unstemmed | Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution |
| title_short | Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution |
| title_sort | genome sequence of the asian tiger mosquito aedes albopictus reveals insights into its biology genetics and evolution |
| url | http://hdl.handle.net/1721.1/105183 |
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