Equilibrium and dynamic design principles for binding molecules engineered for reagentless biosensors
Reagentless biosensors rely on the interaction of a binding partner and its target to generate a change in fluorescent signal using an environment-sensitive fluorophore or Förster resonance energy transfer. Binding affinity can exert a significant influence on both the equilibrium and the dynamic re...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2016
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| Online Access: | http://hdl.handle.net/1721.1/105345 https://orcid.org/0000-0002-5749-7869 https://orcid.org/0000-0002-1801-5548 https://orcid.org/0000-0003-2398-5896 |