Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes
The identification of biologically significant variants in cancer genomes is critical to therapeutic discovery, but it is limited by the statistical power needed to discern driver from passenger. Independent biological data can be used to filter cancer exomes and increase statistical power. Large ge...
Main Authors: | Pritchard, Justin R., Zhao, Boyang |
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Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2016
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Online Access: | http://hdl.handle.net/1721.1/105412 https://orcid.org/0000-0003-4610-1707 |
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