Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism

In experimental science, organisms are usually studied in isolation, but in the wild they compete and cooperate in complex communities. We report a system for cross-kingdom communication by which bacteria heritably transform yeast metabolism. An ancient biological circuit blocks yeast from using ot...

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Bibliographic Details
Main Authors: Jarosz, Daniel F., Walker, Gordon A., Ung, W. Lloyd, Lancaster, Alex K., Rotem, Assaf, Weitz, David A., Bisson, Linda F., Brown, Jessica Conrad, Lindquist, Susan, Datta, Manoshi Sen, Chang, Amelia N., Newby, Gregory Arthur
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105722
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0001-6843-9843
https://orcid.org/0000-0002-1999-0169