A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation
A fundamental goal of genomics is to identify the complete set of expressed proteins. Automated annotation strategies rely on assumptions about protein-coding sequences (CDSs), e.g., they are conserved, do not overlap, and exceed a minimum length. However, an increasing number of newly discovered pr...
Main Authors: | Fields, Alexander P., Rodriguez, Edwin H., Jovanovic, Marko, Stern-Ginossar, Noam, Haas, Brian J., Mertins, Philipp, Raychowdhury, Raktima, Hacohen, Nir, Carr, Steven A., Ingolia, Nicholas T., Regev, Aviv, Weissman, Jonathan S. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/105729 https://orcid.org/0000-0001-8567-2049 |
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