Dynamic profiling of the protein life cycle in response to pathogens
Protein expression is regulated by production and degradation of mRNAs and proteins, but their specific relationships remain unknown. We combine measurements of protein production and degradation and mRNA dynamics to build a quantitative genomic model of the differential regulation of gene expressio...
Main Authors: | Jovanovic, M., Mertins, P., Przybylski, D., Chevrier, N., Satija, R., Rodriguez, E. H., Fields, A. P., Schwartz, S., Raychowdhury, R., Mumbach, M. R., Eisenhaure, T., Rabani, M., Gennert, D., Lu, D., Delorey, T., Weissman, J. S., Carr, S. A., Hacohen, N., Regev, Aviv, Rooney, Michael Steven |
---|---|
Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2016
|
Online Access: | http://hdl.handle.net/1721.1/105732 https://orcid.org/0000-0001-8567-2049 |
Similar Items
-
An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling
by: Yosef, Nir, et al.
Published: (2018) -
A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation
by: Fields, Alexander P., et al.
Published: (2016) -
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks
by: Parnas, Oren, et al.
Published: (2017) -
Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli
by: Gat-Viks, Irit, et al.
Published: (2014) -
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
by: Schwartz, Schraga, et al.
Published: (2017)