High-Resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies
Cells control dynamic transitions in transcript levels by regulating transcription, processing, and/or degradation through an integrated regulatory strategy. Here, we combine RNA metabolic labeling, rRNA-depleted RNA-seq, and DRiLL, a novel computational framework, to quantify the level; editing sit...
Main Authors: | Raychowdhury, Raktima, Jovanovic, Marko, Stumpo, Deborah J., Pauli, Andrea, Hacohen, Nir, Schier, Alexander F., Blackshear, Perry J., Friedman, Nir, Amit, Ido, Rabani, Michal, Rooney, Michael Steven, Regev, Aviv |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/105734 https://orcid.org/0000-0001-8567-2049 |
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