Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user o...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Durand, Neva C., Robinson, James T., Shamim, Muhammad S., Machol, Ido, Aiden, Erez Lieberman, Lander, Eric Steven, Mesirov, Jill P.
مؤلفون آخرون: Massachusetts Institute of Technology. Department of Biology
التنسيق: مقال
اللغة:en_US
منشور في: Elsevier 2016
الوصول للمادة أونلاين:http://hdl.handle.net/1721.1/105759
الوصف
الملخص:Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.