Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis
The balance between oxidative and non-oxidative glucose metabolism is essential for a number of pathophysiological processes. By deleting enzymes that affect aerobic glycolysis with different potencies, we examine how modulating glucose metabolism specifically affects hematopoietic and leukemic cel...
Main Authors: | Wang, Ying-Hua, Lee, Dongjun, Yu, Vionnie W.C., Jeanson, Nathaniel T., Clish, Clary B., Cantley, Lewis C., Scadden, David T., Israelsen, William James, Vander Heiden, Matthew G. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/105820 https://orcid.org/0000-0002-6702-4192 |
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